Anti-bacterial Activity and Phytochemical Composition of Extracts of Three Medicinal Asteraceae Species from Burkina Faso
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چکیده
The aim of this study was to investigate anti-bacterial activities and phytochemical composition of three Asteraceae (C. americanum, E. alba and V. colorata) from traditionally medicine of Burkina Faso. Inhibition zone diameters of extracts and minimum inhibitory concentration (MIC) of Gramnegative and Gram-positive strains were determinate using standard methods. Preliminary phytochemical tests and polyphenols contents of extracts were evaluated to explain their anti-bacterial activities.Good diameters of inhibition zones were obtained. E. alba butanol fraction presented best MIC (1.25mg/mL for S. typhimurium (salad), P. mirabilis (ATCC: 35659) and S. aureus (ATCC: 6538); 0.625mg/mL for V. cholerae (water) and 0.3125mg/mL for B. cereus (ATCC: 9144)) for several strains used and the highest in phenolic content (88.88 ± 0.7GAE/100mg of extract). This phytochemical profile would explain the anti-bacterial activities of extracts of plants. Our study shows that C. americanum could be also used for the treatment of some bacterial infection diseases. C. americanum and E. alba are good ways for Burkina Faso future research to isolate new anti-bacterial compounds.
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تاریخ انتشار 2012